Generalized whole-body Patlak parametric imaging for enhanced quantification in clinical PET
نویسندگان
چکیده
منابع مشابه
Generalized whole-body Patlak parametric imaging for enhanced quantification in clinical PET.
We recently developed a dynamic multi-bed PET data acquisition framework to translate the quantitative benefits of Patlak voxel-wise analysis to the domain of routine clinical whole-body (WB) imaging. The standard Patlak (sPatlak) linear graphical analysis assumes irreversible PET tracer uptake, ignoring the effect of FDG dephosphorylation, which has been suggested by a number of PET studies. I...
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Whole-body (WB) dynamic PET has recently demonstrated its potential in translating the quantitative benefits of parametric imaging to the clinic. Post-reconstruction standard Patlak (sPatlak) WB graphical analysis utilizes multi-bed multi-pass PET acquisition to produce quantitative WB images of the tracer influx rate K i as a complimentary metric to the semi-quantitative standardized uptake va...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2015
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/60/22/8643